MCQ Paper No. 13

Please select True or False for the following questions.

1. Regarding 0.9% NaCl

a. 1000mL contains 0.9g of Chloride ions
b. Excessive use is associated with a metabolic acidosis
c. It is first line for use in symptomatic hyponatraemia
d. It's use is preferential over albumin for fluid resuscitation in septic shock
e. 1000mL contains 140mmol of both Na and Cl ions


2. Regarding Thiopentone for cerebral protection:

a. It reduces cerebral oxygen consumption by 60%
b. It is indicated for use when the cause is cardiac arrest
c. It has a greater effect when given before the event
d. It exerts it's effect by reducing cerebral blood flow.
e. It can be used to control seizures refractory to alternative therapy.
3. Dexmedetomidine

a. Is a highly selective alpha-2 antagonist
b. Has a greater amnesic effect than midazolam
c. Requires dose reduction in renal failure
d. At high doses can reduced respiratory drive
e. Requires a loading dose
4. Diabetic ketoacidosis is associated with:

a. A low bicarbonate level
b. A low pCO2
c. Hyperkalaemia
d. Renal failure
e. Partial oxidation of fatty acids
5. Hypovolaemic shock results in:

a. A high ScvO2
b. Increased stroke volume
c. High oxygen extraction ratio
d. Increased systemic vascular resistance
e. increased pulmonary vascular resistance

Leave a comment

4 thoughts on “MCQ Paper No. 13

  • Christopher Smith

    I’m pretty sure 3. a is true

    ‘Dexmedetomidine is the S-enantiomer of the veterinary sedative medetomidine. It is a highly selective α2-adrenoceptor agonist’
    BJA Ed ‘Dexmedetomedine: its use in intensive care medicine and anaesthesia’

  • Rebecca Dooley

    The ESE/ESICM joint guidelines on hyponatraemia 2014 classify symptoms in to ‘moderately severe’ and ‘severe’ only. Otherwise I guess they’re considered asymptomatic. For any patient with symptoms falling into these categories, hypertonic saline is recommended.
    Also, if a patient had – what was traditionally considered – ‘mild’ symptoms of hyponatraemia, we should treat based on cause in any case. If the hyponatraemia and symptoms were caused by SIADH, for example, then fluid restriction would be the correcting measure of choice, not additional fluids.